The “Global Commission to End the Diagnostic Odyssey for Children” is a joint initiative by Shire, Microsoft and Eurordis-Rare Diseases Europe that groups multi-disciplinary experts in order to develop an actionable roadmap to help the rare disease field to shorten the multi-year diagnostic journey. The Commission will address new recommendations focusing on core barriers preventing timely diagnosis and it will be co-chaired by Flemming Ornskov (Chief Executive Officer, Shire), Simon Kos (Chief Medical Officer and Senior Director, Worldwide Health, Microsoft) and Yann Le Cam (Chief Executive Officer, Eurordis-Rare Diseases Europe).